Yankees vs Blue Jays Prediction, Odds & Home Run Pick for Tonight’s MLB Game

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Toronto Blue Jays starter Trey Yesavage profiles well against a New York Yankees squad that has been swing-happy this season, making his strikeout prop appetizing.  

Read on for my Blue Jays vs. Yankees predictions and MLB picks for this Thursday, June 12, matchup. 

Yankees vs Blue Jays predictions

Yankees vs Blue Jays best bet: Trey Yesavage Over 6.5 Ks (+110)

Trey Yesavage is 2-0 against the New York Yankees, throwing 11.2 scoreless innings with 19 strikeouts. His splitter gave this Yankees team fits last season, and the Toronto Blue Jays’ rookie right-hander is poised to baffle those Yankee bats again. 

He limits contact, garnering a .188 xBA, while ranking in the 85th percentile in barrel rates

The Yankees don’t barrel the ball very well, and have the second-highest strikeout rate against right-handers with Yesavage’s pitching arsenal (four-seamer, Splitter, slider).

New York’s offense also owns a league-worst .199 xBA against those pitch types. I’d bet Yesavage O 6.5 strikeouts up to +100.

Covers COVERS INTEL: Yesavage owns a 54% strikeout rate against the Yankees. 

Yankees vs Blue Jays same-game parlay (SGP)

I’m expecting a lot of swings and misses from the Yankees’ bats tonight, so I’ll add Over 0.5 strikeouts to Trent Grisham.

He owns a 37.5% strikeout rating against Yesavages pitch mix, and struck out in 3-of-4 playoff appearances against him. 

I’ll also bet over 0.5 singles for Vladimir Guerrero Jr. He profiles well against Yankees starter Ryan Weathers and has been hitting the ball harder recently, which has led to line drive singles and hard hit balls into the outfield. 

Additionally, 80% of his hits this season have been singles

Yankees vs Blue Jays SGP

  • Trey Yesavage Over 6.5 strikeouts
  • Trent Grisham Over 0.5 strikeouts
  • Vladimir Guerrero Jr. Over 0.5 singles
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Yankees vs Blue Jays home run pick: Kazuma Okamoto (+370)

Weathers has been prone to the longball over his last four starts, surrendering seven bombs in that stretch. 

Kazuma Okamoto’s hitting profile matches up best against Weathers, who uses a four-seamer as his primary pitch. 

The Jays slugger barrels the baseball well and puts power into his swings with a 64% hard-hit rate and a .544 slug against the four-seamer this season

I’ll bet half a unit on this, however, considering the Jays’ inconsistent power numbers all season. 

2026 Transparency record
  • Best bets: 33-33, +4.85 units
  • SGPs: 13-53, +6.35 units
  • HR picks: 9-57, -2.30 units

Yankees vs Blue Jays odds

  • Moneyline: New York -115 | Toronto +104
  • Run line: New York +1.5 (-210) | Toronto -1.5 (+180)
  • Over/Under: Over 8 (-110) | Under 8 (-110)

Yankees vs Blue Jays trend

The Toronto Blue Jays have hit the Game Total Over in 9 of their last 12 games (+5.80 Units / 45% ROI). Find more MLB betting trends for Yankees vs. Blue Jays.

How to watch Yankees vs Blue Jays and game info

Location Rogers Centre, Toronto, ON
Date Friday, 6-12-2026
First pitch 5:37 p.m. ET
TV YES, SN
Yankees starting pitcher Ryan Weathers
(2-4, 3.86 ERA)
Blue Jays starting pitcher Trey Yesavage
(2-3, 3.16 ERA)

Yankees vs Blue Jays latest injuries

Yankees vs Blue Jays weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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