White Sox vs Yankees Prediction, Picks & Odds for Today’s MLB Game

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The Chicago White Sox dropped the first two games of their series with the New York Yankees in blowout fashion. 

While another high-scoring game should be expected, my White Sox vs. Yankees predictions and MLB picks see value backing the road team to keep it close on Thursday, June 18.

Who will win White Sox vs Yankees today: White Sox +1.5 (-140)

New York Yankees lefty Ryan Weathers is in miserable form, conceding at least five runs in four of his last five starts.

A big problem for him has been limiting power. He allowed multiple homers in four of those games, and ranks in the sixth percentile in barrel rate this season.

That spells trouble against the Chicago White Sox. They rank third in wOBA, third in OPS, and tied for first in homers against left-handed pitchers. They have a ton of power.

Their offense gives them an excellent chance of keeping this close. Play White Sox +1.5 to -160.

Covers COVERS INTEL: Weathers has allowed 2.63 homers per nine innings over the last 30 days, most among today’s starting pitchers.

White Sox vs Yankees Over/Under pick: Over 9.5 (-105)

It’ll be a hot day at Yankee Stadium with winds blowing out, creating a good environment for run-generation.

These are two teams well-equipped to take advantage. No team has hit more homers against left-handed pitchers than the White Sox, and no team has hit more homers – period – than the Yankees.

Weathers can’t keep the ball in the bark while Sean Burke has allowed a 50% fly ball rate over the last month. You don’t want to put the ball in the air consistently against a powerful offense in warm conditions.

Play the Over to -115.

Todd Cordell’s 2026 Transparency Record
  • ML/RL bets: 32-27, -2.65 units
  • Over/Under bets: 32-25-2, +3.84 units

White Sox vs Yankees weather

Favorable hitting conditions are expected with temperatures in the high 70s and wind blowing out 10-15 mph.

White Sox vs Yankees odds

  • Moneyline: White Sox +135 | Yankees -155
  • Run line: White Sox +1.5 (-140) | Yankees -1.5 (+120)
  • Over/Under: Over 9.5 (-110) | Under 9.5 (-110)

White Sox vs Yankees trend

The White Sox have hit the Over in 23 of their last 35 games (+11.95 units, 31% ROI). Find more MLB betting trends for White Sox vs. Yankees.

How to watch White Sox vs Yankees and game info

Location Yankee Stadium, Bronx, NY
Date Thursday, June 18, 2026
First pitch 7:05 p.m. ET
TV CHSN, YES
White Sox starting pitcher Sean Burke
(3-4, 4.15 ERA)
Yankees starting pitcher Ryan Weathers
(2-5, 4.36 ERA)

White Sox vs Yankees latest injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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