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A pair of AL Central rivals continue their four-game set tonight as the Cleveland Guardians play host to the Chicago White Sox.
Despite missing Munetaka Murakami for the past month, Chicago continues to hit the ball well, which is part of why I’m backing the White Sox as +114 underdogs.
Find out more in my White Sox vs. Guardians predictions and free MLB picks for Friday, July 3.
Who will win White Sox vs Guardians today: White Sox (+114)
The Chicago White Sox are still without Munetaka Murakami, but that hasn’t slowed them down.
Over the past 30 days, Chicago ranks tied for fifth in the AL in runs scored (122) and fourth in SLG (.435). The White Sox have been red hot this week, averaging 7.28 runs per game while hitting .296 as a team.
Meanwhile, the Cleveland Guardians are last in runs (88), batting average (.218), and OPS (.632) over the past month.
There’s clear value to be had here on Chicago at +114, and I’d play them to +110.
COVERS INTEL: Guardians starter Gavin Williams goes to the curveball often, and the White Sox rank sixth in SLG (.410) and third in wOBA (.320) against that pitch.White Sox vs Guardians Over/Under pick: Over 8.5 (+109)
Both starters have been brutal of late, which should help nullify Cleveland’s sluggish offense. Gavin Williams finished with a 6.04 ERA and 1.42 WHIP in June, while Anthony Kay posted a 6.35 ERA and 1.50 WHIP over that same span.
The Over has cashed in each of the past five starts for both Williams and Kay, while the Over is also 4-1 in the past five games for both clubs.
I’ll play this to +100.
- ML/RL bets: 5-1, +3.18 units
- Over/Under bets: 2-4, -1.9 units
White Sox vs Guardians weather
Temperatures will be humid and sit in the mid-to-upper 80s around first pitch, further buoying our play on the Over at Progressive Field.
White Sox vs Guardians odds
- Moneyline: White Sox +114 | Guardians -126
- Run line: White Sox +1.5 (-183) | Guardians -1.5 (+158)
- Over/Under: Over 8.5 (+109) | Under 8.5 (-121)
White Sox vs Guardians trend
Chicago has hit the team total Over in 24 of its last 35 road games (+12.70 Units / 32% ROI). Find more MLB betting trends for White Sox vs. Guardians.
How to watch White Sox vs Guardians and game info
| Location | Progressive Field, Cleveland, OH |
| Date | Friday, July 3, 2026 |
| First pitch | 7:10 p.m. ET |
| TV | CHSN, WKYC-NBC3 |
| White Sox starting pitcher | Anthony Kay (6-3, 4.50 ERA) |
| Guardians starting pitcher | Gavin Williams (9-4, 3.81 ERA) |
White Sox vs Guardians latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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