Blue Jays vs Cubs Prediction, Odds & Home Run Pick for Today’s MLB Game

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Chicago Cubs shortstop Dansby Swanson draws one of the toughest matchups in baseball today against Dylan Cease, whose elite swing-and-miss arsenal should neutralize the struggling slugger.

Read on for my top Blue Jays vs. Cubs predictions and MLB picks for this Sunday, June 21 matchup. 

Blue Jays vs Cubs predictions

Blue Jays vs Cubs best bet: Dansby Swanson Under 0.5 hits (-130)

Dansby Swanson has been one of the worst hitters in baseball this season with a .177 batting average, while ranking in the second percentile in xBA.

Additionally, his hitting profile does not match up well at all against Toronto Blue Jays starter Dylan Cease, who has elite swing-and-miss stuff. 

Swanson can’t hit the breaking ball this season, owning a .095 average with a 33% whiff rate

That won’t bode well against Cease, who ranks in the 99th percentile in strikeout rate with a 37% whiff rate. 

A lot of his whiffs come from his slider, which is his most-used pitch to right-handed batters, which is also a pitch that Swanson struggles with (.048 batting average, 37% whiff rate). 

Additionally, Swanson is just 1-for-6 against Cease in his career. I’d play this prop up to -140. 

Covers COVERS INTEL: Swanson doesn’t generate much contact against Cease’s two most used pitches, owning a porous .048 average and a 34% whiff rate against the slider and changeup combined.

Blue Jays vs Cubs same-game parlay (SGP)

Cease has electric stuff, leading the American League with 110 Ks. He’s eclipsed today’s number in seven straight starts and owns a 39% strikeout rate against this Chicago Cubs lineup. 

George Springer is turning a corner with a 1.089 OPS over his last nine games, and profiles well against Shota Imanaga, who’s primarily a fastball pitcher.

Springer owns a .291 xBA over the last three seasons with a .613 xSLG. 

Blue Jays vs Cubs SGP

  • Dansby Swanson Under 0.5 hits
  • Dylan Cease Over 6.5 strikeouts
  • George Springer Over 1.5 total bases
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Blue Jays vs Cubs home run pick: Kazuma Okamoto (+365)

Kazuma Okamoto‘s hitting profile matches up perfectly against Imanaga’s stuff. 

The Cubs starter throws a heavy dose of the fastball and gets barreled up at a 10.4% rate. The Jays third baseman barrels the ball better than anyone in the Blue Jays lineup (13.5%) while possessing a 63.2% hard-hit rate against the four-seamer. 

Additionally, Imanaga has allowed 14 home runs over 15 outings this season. 

This is a half-unit wager.

2026 Transparency record
  • Best bets: 35-39, +0.75 units
  • SGPs: 14-60, +2.15 units
  • HR picks: 12-62, +1.8 units

Blue Jays vs Cubs odds

  • Moneyline: Toronto -116 | Chicago +102
  • Run line: Toronto -1.5 | Chicago +1.5
  • Over/Under: Over 7 | Under 7

Blue Jays vs Cubs trend

The Blue Jays have hit the moneyline in nine of their last 14 away games (+6.00 Units / 41% ROI). Find more MLB betting trends for Blue Jays vs. Cubs.

How to watch Blue Jays vs Cubs and game info

Location Wrigley Field, Chicago, IL
Date Sunday, 6-21-2026
First pitch 2:20 p.m. ET
TV MARQ, Sportsnet
Blue Jays starting pitcher Dylan Cease
(4-3, 2.71 ERA)
Cubs starting pitcher Shota Imanaga
(4-6, 4.26 ERA)

Blue Jays vs Cubs latest injuries

Blue Jays vs Cubs weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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