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The Tony Vitello era is off to an inauspicious start as the San Francisco Giants are 3-6 with a National League-worst -22 run differential.
Logan Webb takes the bump on Sunday, however, and the ace hopes to turn the tide against the New York Mets.
See why I’m backing the home team with my Mets vs. Giants predictions and MLB picks for the series finale on Sunday, April 5.
Who will win Mets vs Giants today: Giants (-113)
Logan Webb is a beast at Oracle Park, sporting a career 2.92 ERA and 2.71 FIP across a massive sample size of 552 ⅓ IP.
The New York Mets have the better lineup, but the gap closes with Juan Soto likely out of the lineup after receiving an MRI on Saturday.
It’s been a slow start offensively for the San Francisco Giants, but things will pick up sooner or later, as 1–7 in the lineup is certainly league-caliber.
Kodai Senga has never figured out his walk problem (11.1% career walk rate) and is a beatable opponent.
COVERS INTEL: Senga’s issues have been exacerbated on the road, where he has a career 1.33 WHIP and 4.17 FIP. His K-BB% drops down to 11.6%.Mets vs Giants Over/Under pick: Under 7.5 (-117)
Webb’s strong performance at home, combined with a likely Soto-less Mets lineup, means New York likely won’t have another offensive outburst after plating 19 runs in the last two games.
San Francisco has been the worst team in the league against RHP (44 wRC+) and has scored three or fewer runs in seven of their nine contests this season.
Each of the first three games of this series cashed the Over 7.5, but here’s betting on an Under in the finale. The Mets have hit the Under in 28 of their last 45 away games, and Oracle’s Park is a pitcher’s best friend.
- ML/RL bets: 2-0, +2.0 units
- Over/Under bets: 1-2, -1.09 units
Mets vs Giants odds
- Moneyline: New York +113 | San Francisco -124
- Run line: New York +1.5 (-215) | San Francisco -1.5 (+183)
- Over/Under: Over 7.5 (-105) | Under 7.5 (-115)
Mets vs Giants trend
Logan Webb has had a winning record at home in each of the last five seasons. Find more MLB betting trends for Mets vs. Giants.
How to watch Mets vs Giants and game info
| Location | Oracle Park, San Francisco, CA |
| Date | Sunday, April 5, 2026 |
| First pitch | 4:05 p.m. ET |
| TV | SNY, NBC Sports Bay Area |
| Mets starting pitcher | Kodai Senga (0-1, 3.00 ERA) |
| Giants starting pitcher | Logan Webb (1-1, 7.36 ERA) |
Mets vs Giants latest injuries
Mets vs Giants weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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